Study on detection methods for triclocarban

Triclocarban (TCC) is used in a wide range of household and personal care products, such as soaps, shampoos, creams, mouthwash, and toothpaste. However, TCC is found to have harmful effects on humans and other animals because of its increasing methemoglobinemia. TCC exposure enhances the estradiol-dependent or testosterone-dependent activation of the estrogen receptor-responsive and the androgen receptor-responsive gene expression in human ovary cells. The potential risk to the environment and human health generated by TCC is currently drawing considerable attention worldwide. Therefore, the development of rapid, sensitive, and reliable analytical methods is necessary to determine the presence of TCC in environmental samples for safety evaluation. In this article the studies of detection methods for TCC in recent years are reviewed.